Use of Rituximab in Autoimmune Hemolytic Anemia Associated with Non-Hodgkin Lymphomas
Joint Authors
Longinotti, Maurizio
Fozza, Claudio
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The association between non-Hodgkin lymphomas and autoimmune disorders is a well-known event.
Also autoimmune hemolytic anemia (AHA), although much more frequent in patients with chronic lymphocytic leukemia (CLL), has been described in this group of patients.
In recent years, among the more traditional therapeutic options, rituximab, an anti-CD20 monoclonal antibody, has shown interesting results in the treatment of primary AHA.
Although this drug has been frequently used for AHA in patients with CLL, much less data are available on its use in NHL patients.
However, considering that the main pathogenetic mechanism of AHA in course of lymphoproliferative disorders seems to be an antibody production directly or indirectly mediated by the neoplastic clone, this monoclonal antibody represents an ideal therapeutic approach.
In this paper we will briefly describe some biological and clinical features of NHL-patients with AHA.
We will then analyze some studies focusing on rituximab in primary AHA, finally reviewing the available literature on the use of this drug in NHL related AHA.
American Psychological Association (APA)
Fozza, Claudio& Longinotti, Maurizio. 2011. Use of Rituximab in Autoimmune Hemolytic Anemia Associated with Non-Hodgkin Lymphomas. Advances in Hematology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-511560
Modern Language Association (MLA)
Fozza, Claudio& Longinotti, Maurizio. Use of Rituximab in Autoimmune Hemolytic Anemia Associated with Non-Hodgkin Lymphomas. Advances in Hematology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-511560
American Medical Association (AMA)
Fozza, Claudio& Longinotti, Maurizio. Use of Rituximab in Autoimmune Hemolytic Anemia Associated with Non-Hodgkin Lymphomas. Advances in Hematology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-511560
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511560