Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis : Prevalence and Determinants
Joint Authors
Gabreels, Bas A.
Groeneveld, Marc
Jukema, Jan Wouter
de Bie, Mihály K.
Bax, Jeroen J.
Gaasbeek, André
Delgado, Victoria
Rabelink, Ton J.
Ajmone Marsan, Nina
Schalij, Martin J.
Source
International Journal of Nephrology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Diastolic dysfunction is common among dialysis patients and is associated with increased morbidity and mortality.
Novel echocardiographic speckle tracking strain analysis permits accurate assessment of left ventricular diastolic function, independent of loading conditions and taking all myocardial segments into account.
The aim of the study was to evaluate the prevalence of diastolic dysfunction in chronic dialysis patients using this novel technique, and to identify its determinants among clinical and echocardiographic variables.
Methods.
Patients currently enrolled in the ICD2 study protocol were included for this analysis.
Next to conventional echo measurements diastolic function was also assessed by global diastolic strain rate during isovolumic relaxation (SRIVR).
Results.
A total of 77 patients were included (age 67±8 years, 74% male).
When defined as E/SRIVR ≥236, the prevalence of diastolic dysfunction was higher compared to more conventional measurements (48% versus 39%).
Left ventricular mass (OR 1.02, 95% CI 1.00–1.04, P=0.014) and pulse wave velocity (OR 1.34, 95% CI 1.07–1.68, P=0.01) were independent determinants of diastolic dysfunction.
Conclusion.
Diastolic dysfunction is highly prevalent among dialysis patients and might be underestimated using conventional measurements.
Left ventricular mass and pulse wave velocity were the only determinants of diastolic dysfunction in these patients.
American Psychological Association (APA)
de Bie, Mihály K.& Ajmone Marsan, Nina& Gaasbeek, André& Bax, Jeroen J.& Groeneveld, Marc& Gabreels, Bas A.…[et al.]. 2012. Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis : Prevalence and Determinants. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-511864
Modern Language Association (MLA)
de Bie, Mihály K.…[et al.]. Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis : Prevalence and Determinants. International Journal of Nephrology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-511864
American Medical Association (AMA)
de Bie, Mihály K.& Ajmone Marsan, Nina& Gaasbeek, André& Bax, Jeroen J.& Groeneveld, Marc& Gabreels, Bas A.…[et al.]. Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis : Prevalence and Determinants. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-511864
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511864