![](/images/graphics-bg.png)
Prevalence of Oral Manifestations and Their Association with CD4CD8 Ratio and HIV Viral Load in South India
Joint Authors
Nagpal, Archna
Keerthilatha, Pai M.
Sharma, Gaurav
Source
International Journal of Dentistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The objective of the present research was to determine the prevalence of oral manifestations in an HIV infected population from south India and evaluate their association with HIV viral load and CD4/CD8 ratio.
Intraoral examination of 103 patients, whose CD4/CD8 ratio was available, were conducted.
HIV viral loads were available for thirty patients only.
The prevalence of oral manifestations was 80.6% (83/103).
The most common oromucosal lesion was erythematous candidiasis (EC) (38.8%) followed by melanotic hyperpigmentation (35.9%).
Patients having any oral manifestation had a mean CD4/CD8 ratio of 0.24.
EC had positive predictive value of 85.0% for CD4/CD8 ratio <0.30.
The prevalence of oral manifestations in patients taking ART was lesser (78.6%) as compared to patients not taking ART (82%).
Patients having any oral manifestation had a higher HIV viral load as compared to patients not having any oral manifestations (P<0.05).
Pseudomembranous candidiasis (PC) was significantly associated with higher HIV viral loads (>20,000 copies/mL) (P<0.05).
Patients having EC had 4 times greater chance of having CD4/CD8 ratio <0.30.
PC can be considered as a marker of immune suppression (HIV viral load >20,000 copies/mL).
American Psychological Association (APA)
Sharma, Gaurav& Keerthilatha, Pai M.& Nagpal, Archna. 2011. Prevalence of Oral Manifestations and Their Association with CD4CD8 Ratio and HIV Viral Load in South India. International Journal of Dentistry،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-511942
Modern Language Association (MLA)
Sharma, Gaurav…[et al.]. Prevalence of Oral Manifestations and Their Association with CD4CD8 Ratio and HIV Viral Load in South India. International Journal of Dentistry No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-511942
American Medical Association (AMA)
Sharma, Gaurav& Keerthilatha, Pai M.& Nagpal, Archna. Prevalence of Oral Manifestations and Their Association with CD4CD8 Ratio and HIV Viral Load in South India. International Journal of Dentistry. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-511942
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511942