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Eleucine indica Possesses Antioxidant, Antibacterial and Cytotoxic Properties
Joint Authors
Abdul, Ahmad Bustamam
Peng, Chew Yuan
Abdel Wahab, Siddig Ibrahim
Alzubairi, Adel Sharaf
Mohan, Syam
Elhassan, Manal Mohamed
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The use of evidence-based complementary and alternative medicine is increasing rapidly.
Eleucine indica (EI) is traditionally used in ailments associated with liver and kidneys.
The therapeutic benefit of the medicinal plants is often attributed to their antioxidant properties.
Therefore, the aim of this study was to screen the hexane, dicholoromethane, ethyl acetate (EA) and methanol extracts (MeTH) of EI for their antioxidant, antibacterial and anti-cancer effects using total phenolic contents (TPCs) and DPPH, disc diffusion method and MTT cytotoxicity assays, respectively.
The MeTH was showed to have the highest TPC and scavenging activity (77.7%) on DPPH assay, followed by EA (64.5%), hexane (47.19%) and DCM (40.83%) extracts, whereas the MeTH showed no inhibitory effect on all tested bacteria strains.
However, the EA extract exhibited a broad spectrum antibacterial activity against all tested bacteria except Bacillus subtilis, in which this bacterium was found to be resistant to all EI extracts.
Meanwhile, hexane extract was demonstrated to have a remarkable antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, while the dicholoromethane extract did not exhibit significant activity against P.
aeruginosa.
None of the extracts showed significant cytotoxic activity towards MCF-7, HT-29 and CEM-SS human cancer cell lines after 72 h incubation time (IC50 > 30 μg/ml).
These results demonstrate that the extract prepared from the EI possesses antioxidant activity in vitro in addition to antibacterial properties.
Further investigations are needed to verify the antioxidant effects in vitro and in vivo.
American Psychological Association (APA)
Alzubairi, Adel Sharaf& Abdul, Ahmad Bustamam& Abdel Wahab, Siddig Ibrahim& Peng, Chew Yuan& Mohan, Syam& Elhassan, Manal Mohamed. 2011. Eleucine indica Possesses Antioxidant, Antibacterial and Cytotoxic Properties. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-512042
Modern Language Association (MLA)
Alzubairi, Adel Sharaf…[et al.]. Eleucine indica Possesses Antioxidant, Antibacterial and Cytotoxic Properties. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-512042
American Medical Association (AMA)
Alzubairi, Adel Sharaf& Abdul, Ahmad Bustamam& Abdel Wahab, Siddig Ibrahim& Peng, Chew Yuan& Mohan, Syam& Elhassan, Manal Mohamed. Eleucine indica Possesses Antioxidant, Antibacterial and Cytotoxic Properties. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-512042
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512042