Sexual Transmission of XMRV : A Potential Infection Route
Joint Authors
Onlamoon, Nattawat
Sharma, Prachi
Schochetman, Gerald
Villinger, François
Rogers, Kenneth A.
Molinaro, Ross J.
Hackett, John
Silverman, Robert H.
Suppiah, Suganthi
Klein, Eric A.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Although XMRV dissemination in humans is a matter of debate, the prostate of select patients seem to harbor XMRV, which raises questions about its potential route of transmission.
We established a model of infection in rhesus macaques inoculated with XMRV.
In spite of the intravenous inoculation, all infected macaques exhibited readily detectable XMRV signal in the reproductive tract of all 4 males and 1 female during both acute and chronic infection stages.
XMRV showed explosive growth in the acini of prostate during acute but not chronic infection.
In seminal vesicles, epididymis, and testes, XMRV protein production was detected throughout infection in interstitial or epithelial cells.
In the female monkey, epithelial cells in the cervix and vagina were also positive for XMRV gag.
The ready detection of XMRV in the reproductive tract of male and female macaques infected intravenously suggests the potential for sexual transmission for XMRV.
American Psychological Association (APA)
Sharma, Prachi& Rogers, Kenneth A.& Suppiah, Suganthi& Molinaro, Ross J.& Onlamoon, Nattawat& Hackett, John…[et al.]. 2011. Sexual Transmission of XMRV : A Potential Infection Route. Advances in Virology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-512062
Modern Language Association (MLA)
Sharma, Prachi…[et al.]. Sexual Transmission of XMRV : A Potential Infection Route. Advances in Virology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-512062
American Medical Association (AMA)
Sharma, Prachi& Rogers, Kenneth A.& Suppiah, Suganthi& Molinaro, Ross J.& Onlamoon, Nattawat& Hackett, John…[et al.]. Sexual Transmission of XMRV : A Potential Infection Route. Advances in Virology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-512062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512062