Development of Viral Vectors for Gene Therapy for Chronic Pain
Joint Authors
He, Xiaohua
Liu, Wanhong
Huang, Yu
Liu, Xin
Liu, Zhongchun
Dong, Lanlan
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Chronic pain is a major health concern that affects millions of people.
There are no adequate long-term therapies for chronic pain sufferers, leading to significant cost for both society and the individual.
The most commonly used therapy for chronic pain is the application of opioid analgesics and nonsteroidal anti-inflammatory drugs, but these drugs can lead to addiction and may cause side effects.
Further studies of the mechanisms of chronic pain have opened the way for development of new treatment strategies, one of which is gene therapy.
The key to gene therapy is selecting safe and highly efficient gene delivery systems that can deliver therapeutic genes to overexpress or suppress relevant targets in specific cell types.
Here we review several promising viral vectors that could be applied in gene transfer for the treatment of chronic pain and further discuss the possible mechanisms of genes of interest that could be delivered with viral vectors for the treatment of chronic pain.
American Psychological Association (APA)
Huang, Yu& Liu, Xin& Dong, Lanlan& Liu, Zhongchun& He, Xiaohua& Liu, Wanhong. 2011. Development of Viral Vectors for Gene Therapy for Chronic Pain. Pain Research and Treatment،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-512190
Modern Language Association (MLA)
Huang, Yu…[et al.]. Development of Viral Vectors for Gene Therapy for Chronic Pain. Pain Research and Treatment No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-512190
American Medical Association (AMA)
Huang, Yu& Liu, Xin& Dong, Lanlan& Liu, Zhongchun& He, Xiaohua& Liu, Wanhong. Development of Viral Vectors for Gene Therapy for Chronic Pain. Pain Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-512190
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512190