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Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases
Joint Authors
Mizoguchi, Izuru
Qu, Ning
Xu, Mingli
Kawakami, Yutaka
Kaneko, Kotaro
Furusawa, Jun-ichi
Mizuguchi, Junichiro
Yoshimoto, Takayuki
Itoh, Masahiro
Watanabe, Kazunori
Source
Clinical and Developmental Immunology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-14
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
T-helper 17 (Th17) cells are characterized by producing interleukin-17 (IL-17, also called IL-17A), IL-17F, IL-21, and IL-22 and potentially TNF-α and IL-6 upon certain stimulation.
IL-23, which promotes Th17 cell development, as well as IL-17 and IL-22 produced by the Th17 cells plays essential roles in various inflammatory diseases, such as experimental autoimmune encephalomyelitis, rheumatoid arthritis, colitis, and Concanavalin A-induced hepatitis.
In this review, we summarize the characteristics of the functional role of Th17 cells, with particular focus on the Th17 cell-related cytokines such as IL-17, IL-22, and IL-23, in mouse models and human inflammatory diseases.
American Psychological Association (APA)
Qu, Ning& Xu, Mingli& Mizoguchi, Izuru& Furusawa, Jun-ichi& Kaneko, Kotaro& Watanabe, Kazunori…[et al.]. 2013. Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases. Clinical and Developmental Immunology،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-512217
Modern Language Association (MLA)
Qu, Ning…[et al.]. Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases. Clinical and Developmental Immunology No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-512217
American Medical Association (AMA)
Qu, Ning& Xu, Mingli& Mizoguchi, Izuru& Furusawa, Jun-ichi& Kaneko, Kotaro& Watanabe, Kazunori…[et al.]. Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases. Clinical and Developmental Immunology. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-512217
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512217