Region-Based PDEs for Cells Counting and Segmentation in 3D+Time Images of Vertebrate Early Embryogenesis
Joint Authors
Rizzi, Barbara
Sarti, Alessandro
Source
International Journal of Biomedical Imaging
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-10-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
This paper is devoted to the segmentation of cell nuclei from time lapse confocal microscopy images, taken throughout early Zebrafish embryogenesis.
The segmentation allows to identify and quantify the number of cells in the animal model.
This kind of information is relevant to estimate important biological parameters such as the cell proliferation rate in time and space.
Our approach is based on the active contour model without edges.
We compare two different formulations of the model equation and evaluate their performances in segmenting nuclei of different shapes and sizes.
Qualitative and quantitative comparisons are performed on both synthetic and real data, by means of suitable gold standard.
The best approach is then applied on a number of time lapses for the segmentation and counting of cells during the development of a zebrafish embryo between the sphere and the shield stage.
American Psychological Association (APA)
Rizzi, Barbara& Sarti, Alessandro. 2009. Region-Based PDEs for Cells Counting and Segmentation in 3D+Time Images of Vertebrate Early Embryogenesis. International Journal of Biomedical Imaging،Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-512243
Modern Language Association (MLA)
Rizzi, Barbara& Sarti, Alessandro. Region-Based PDEs for Cells Counting and Segmentation in 3D+Time Images of Vertebrate Early Embryogenesis. International Journal of Biomedical Imaging No. 2009 (2009), pp.1-9.
https://search.emarefa.net/detail/BIM-512243
American Medical Association (AMA)
Rizzi, Barbara& Sarti, Alessandro. Region-Based PDEs for Cells Counting and Segmentation in 3D+Time Images of Vertebrate Early Embryogenesis. International Journal of Biomedical Imaging. 2009. Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-512243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512243