Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction
Joint Authors
Song, Qing
Xie, Lixin
Liu, Changting
Feng, Lin
Kang, Hongjun
Liang, Zhixin
Jia, Yanhong
Zhang, Xingang
Feng, Dan
Su, Longxiang
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
To describe the dynamics changes of sCD163, soluble serum triggering receptor expressed on myeloid cells-1 (sTREM-1), procalcitonin (PCT), and C-reactive protein (CRP) during the course of sepsis, as well as their outcome prediction.
Patients and Methods.
An SIRS group (30 cases) and a sepsis group (100 cases) were involved in this study.
Based on a 28-day survival, the sepsis was further divided into the survivors’ and nonsurvivors’ groups.
Serum sTREM-1, sCD163, PCT, CRP, and WBC counts were tested on days 1, 3, 5, 7, 10, and 14.
Results.
On the ICU admission, the sepsis group displayed higher levels of sTREM-1, sCD163, PCT, and CRP than the SIRS group (P<0.05).
Although PCT and sTREM-1 are good markers to identify severity, sTREM-1 is more reliable, which proved to be a risk factor related to sepsis.
During a 14-day observation, sCD163, sTREM-1, PCT, and SOFA scores continued to climb among nonsurvivors, while their WBC and CRP went down.
Both sCD163 and SOFA scores are risk factors impacting the survival time.
Conclusion.
With regard to sepsis diagnosis and severity, sTREM-1 is more ideal and constitutes a risk factor.
sCD163 is of a positive value in dynamic prognostic assessment and may be taken as a survival-impacting risk factor.
American Psychological Association (APA)
Su, Longxiang& Feng, Lin& Song, Qing& Kang, Hongjun& Zhang, Xingang& Liang, Zhixin…[et al.]. 2013. Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-512316
Modern Language Association (MLA)
Su, Longxiang…[et al.]. Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction. Mediators of Inflammation No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-512316
American Medical Association (AMA)
Su, Longxiang& Feng, Lin& Song, Qing& Kang, Hongjun& Zhang, Xingang& Liang, Zhixin…[et al.]. Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-512316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512316