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Parasite Mitogen-Activated Protein Kinases as Drug Discovery Targets to Treat Human Protozoan Pathogens
Joint Authors
Murthy, Kruthi
Pandeswara, Srilakshmi
Ludwig, Sara M.
Brumlik, Michael J.
Curiel, Tyler J.
Source
Journal of Signal Transduction
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-27
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Protozoan pathogens are a highly diverse group of unicellular organisms, several of which are significant human pathogens.
One group of protozoan pathogens includes obligate intracellular parasites such as agents of malaria, leishmaniasis, babesiosis, and toxoplasmosis.
The other group includes extracellular pathogens such as agents of giardiasis and amebiasis.
An unfortunate unifying theme for most human protozoan pathogens is that highly effective treatments for them are generally lacking.
We will review targeting protozoan mitogen-activated protein kinases (MAPKs) as a novel drug discovery approach towards developing better therapies, focusing on Plasmodia, Leishmania, and Toxoplasma, about which the most is known.
American Psychological Association (APA)
Brumlik, Michael J.& Pandeswara, Srilakshmi& Ludwig, Sara M.& Murthy, Kruthi& Curiel, Tyler J.. 2011. Parasite Mitogen-Activated Protein Kinases as Drug Discovery Targets to Treat Human Protozoan Pathogens. Journal of Signal Transduction،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-512505
Modern Language Association (MLA)
Brumlik, Michael J.…[et al.]. Parasite Mitogen-Activated Protein Kinases as Drug Discovery Targets to Treat Human Protozoan Pathogens. Journal of Signal Transduction No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-512505
American Medical Association (AMA)
Brumlik, Michael J.& Pandeswara, Srilakshmi& Ludwig, Sara M.& Murthy, Kruthi& Curiel, Tyler J.. Parasite Mitogen-Activated Protein Kinases as Drug Discovery Targets to Treat Human Protozoan Pathogens. Journal of Signal Transduction. 2011. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-512505
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512505