In Vivo Computed Tomography as a Research Tool to Investigate Asthma and COPD : Where Do We Stand?
Joint Authors
Dournes, Gaël
Montaudon, Michel
Laurent, François
Berger, Patrick
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-11
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Computed tomography (CT) is a clinical tool widely used to assess and followup asthma and chonic obstructive pulmonary disease (COPD) in humans.
Strong efforts have been made the last decade to improve this technique as a quantitative research tool.
Using semiautomatic softwares, quantification of airway wall thickness, lumen area, and bronchial wall density are available from large to intermediate conductive airways.
Skeletonization of the bronchial tree can be built to assess its three-dimensional geometry.
Lung parenchyma density can be analysed as a surrogate of small airway disease and emphysema.
Since resident cells involve airway wall and lung parenchyma abnormalities, CT provides an accurate and reliable research tool to assess their role in vivo.
This litterature review highlights the most recent advances made to assess asthma and COPD with CT, and also their drawbacks and the place of CT in clarifying the complex physiopathology of both diseases.
American Psychological Association (APA)
Dournes, Gaël& Montaudon, Michel& Berger, Patrick& Laurent, François. 2012. In Vivo Computed Tomography as a Research Tool to Investigate Asthma and COPD : Where Do We Stand?. Journal of Allergy،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-512551
Modern Language Association (MLA)
Dournes, Gaël…[et al.]. In Vivo Computed Tomography as a Research Tool to Investigate Asthma and COPD : Where Do We Stand?. Journal of Allergy No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-512551
American Medical Association (AMA)
Dournes, Gaël& Montaudon, Michel& Berger, Patrick& Laurent, François. In Vivo Computed Tomography as a Research Tool to Investigate Asthma and COPD : Where Do We Stand?. Journal of Allergy. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-512551
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512551