Diagnosing Growth Hormone Deficiency in Adults
Joint Authors
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Adult growth hormone (GH) deficiency is a recognised syndrome associated with adverse phenotypic, metabolic, and quality-of-life features which improve in many patients when GH is substituted.
The appropriate selection of patients at risk of growth hormone deficiency (GHD) is the crucial first step in arriving at a correct diagnosis.
Although multiple diagnostic modalities are available including a 24-hour serum GH profile, stimulated GH levels, and insulin-like growth factor-1 (IGF-1) levels, the use of dynamic tests for GH reserves is required in most cases.
This paper discusses the utility and drawbacks of the various testing modalities with reference to international guidelines.
Regardless of the test chosen, clinical pitfalls including age and obesity must be taken into account.
In addition, there is considerable analytical variation in the biochemical measurements of GH and IGF-1 which must be considered before making a diagnosis of GHD in adulthood.
American Psychological Association (APA)
Glynn, Nigel& Agha, Amar. 2012. Diagnosing Growth Hormone Deficiency in Adults. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-512573
Modern Language Association (MLA)
Glynn, Nigel& Agha, Amar. Diagnosing Growth Hormone Deficiency in Adults. International Journal of Endocrinology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-512573
American Medical Association (AMA)
Glynn, Nigel& Agha, Amar. Diagnosing Growth Hormone Deficiency in Adults. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-512573
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512573