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Intestinal Fluid and Glucose Transport in Wistar Rats following Chronic Consumption of Fresh or Oxidised Palm Oil Diet
Joint Authors
Okwari, Obem O.
Obembe, Agona O.
Antai, Atim B.
Osim, Eme E.
Owu, Daniel U.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Chronic ingestion of thermoxidized palm oil causes functional derangement of various tissues.
This study was therefore carried out to determine the effect of chronic ingestion of thermoxidized and fresh palm oil diets on intestinal fluid and glucose absorption in rats using the everted sac technique.
Thirty Wistar rats were divided into three groups of 10 rats per group.
The first group was the control and was fed on normal rat chow while the second (FPO) and third groups (TPO) were fed diet containing either fresh or thermoxidized palm oil (15% wt/wt) for 14 weeks.
Villus height and crypt depth were measured.
The gut fluid uptake and gut glucose uptake were significantly (P<.001) lower in the TPO group than those in the FPO and control groups, respectively.
The villus height in the TPO was significantly (P<.01) lower than that in FPO and control.
The villus depth in TPO was significantly (P<.05) higher than that in FPO and control groups, respectively.
These results suggest that ingestion of thermoxidized palm oil and not fresh palm oil may lead to distortion in villus morphology with a concomitant malabsorption of fluid and glucose in rats due to its harmful free radicals.
American Psychological Association (APA)
Obembe, Agona O.& Owu, Daniel U.& Okwari, Obem O.& Antai, Atim B.& Osim, Eme E.. 2010. Intestinal Fluid and Glucose Transport in Wistar Rats following Chronic Consumption of Fresh or Oxidised Palm Oil Diet. ISRN Gastroenterology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-512600
Modern Language Association (MLA)
Obembe, Agona O.…[et al.]. Intestinal Fluid and Glucose Transport in Wistar Rats following Chronic Consumption of Fresh or Oxidised Palm Oil Diet. ISRN Gastroenterology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-512600
American Medical Association (AMA)
Obembe, Agona O.& Owu, Daniel U.& Okwari, Obem O.& Antai, Atim B.& Osim, Eme E.. Intestinal Fluid and Glucose Transport in Wistar Rats following Chronic Consumption of Fresh or Oxidised Palm Oil Diet. ISRN Gastroenterology. 2010. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-512600
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512600