Impact of Lipid Nutrition on Neural StemProgenitor Cells
Joint Authors
Osumi, Noriko
Kimura, Ryuichi
Sakayori, Nobuyuki
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-23
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
The neural system originates from neural stem/progenitor cells (NSPCs).
Embryonic NSPCs first proliferate to increase their numbers and then produce neurons and glial cells that compose the complex neural circuits in the brain.
New neurons are continually produced even after birth from adult NSPCs in the inner wall of the lateral ventricle and in the hippocampal dentate gyrus.
These adult-born neurons are involved in various brain functions, including olfaction-related functions, learning and memory, pattern separation, and mood control.
NSPCs are regulated by various intrinsic and extrinsic factors.
Diet is one of such important extrinsic factors.
Of dietary nutrients, lipids are important because they constitute the cell membrane, are a source of energy, and function as signaling molecules.
Metabolites of some lipids can be strong lipid mediators that also regulate various biological activities.
Recent findings have revealed that lipids are important regulators of both embryonic and adult NSPCs.
We and other groups have shown that lipid signals including fat, fatty acids, their metabolites and intracellular carriers, cholesterol, and vitamins affect proliferation and differentiation of embryonic and adult NSPCs.
A better understanding of the NSPCs regulation by lipids may provide important insight into the neural development and brain function.
American Psychological Association (APA)
Sakayori, Nobuyuki& Kimura, Ryuichi& Osumi, Noriko. 2013. Impact of Lipid Nutrition on Neural StemProgenitor Cells. Stem Cells International،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-512667
Modern Language Association (MLA)
Sakayori, Nobuyuki…[et al.]. Impact of Lipid Nutrition on Neural StemProgenitor Cells. Stem Cells International No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-512667
American Medical Association (AMA)
Sakayori, Nobuyuki& Kimura, Ryuichi& Osumi, Noriko. Impact of Lipid Nutrition on Neural StemProgenitor Cells. Stem Cells International. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-512667
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512667