New Oral Anticoagulants in the Treatment of Pulmonary Embolism : Efficacy, Bleeding Risk, and Monitoring
Joint Authors
Rudd, Kelly M.
Phillips, Elizabeth (Lisa) M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Anticoagulation therapy is mandatory in patients with pulmonary embolism to prevent significant morbidity and mortality.
The mainstay of therapy has been vitamin-K antagonist therapy bridged with parenteral anticoagulants.
The recent approval of new oral anticoagulants (NOACs: apixaban, dabigatran, and rivaroxaban) has generated significant interest in their role in managing venous thromboembolism, especially pulmonary embolism due to their improved pharmacokinetic and pharmacodynamic profiles, predictable anticoagulant response, and lack of required efficacy monitoring.
This paper addresses the available literature, on-going clinical trials, highlights critical points, and discusses potential advantages and disadvantages of the new oral anticoagulants in patients with pulmonary embolism.
American Psychological Association (APA)
Rudd, Kelly M.& Phillips, Elizabeth (Lisa) M.. 2013. New Oral Anticoagulants in the Treatment of Pulmonary Embolism : Efficacy, Bleeding Risk, and Monitoring. Thrombosis،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-512689
Modern Language Association (MLA)
Rudd, Kelly M.& Phillips, Elizabeth (Lisa) M.. New Oral Anticoagulants in the Treatment of Pulmonary Embolism : Efficacy, Bleeding Risk, and Monitoring. Thrombosis No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-512689
American Medical Association (AMA)
Rudd, Kelly M.& Phillips, Elizabeth (Lisa) M.. New Oral Anticoagulants in the Treatment of Pulmonary Embolism : Efficacy, Bleeding Risk, and Monitoring. Thrombosis. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-512689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512689