Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with α-Diimine and Quinoxaline Ligands
Joint Authors
Dagas, Constantinos
Mitsopoulou, Christiana A.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The complex [ReOCl3pq] (1) (where pq = 2-(2′pyridyl)quinoxaline) has been synthesized and fully characterized by UV-Vis, FTIR, 1 and 2D NMR, and cyclic voltammetry (CV).
The DNA-binding properties of the complex 1 as well as of the compounds [ReOCl3bpy] (2), [ReOCl3phen] (3), and pq (4) were investigated by UV-spectrophotometric (melting curves), CV (cyclic voltammetry), and viscosity measurements.
Experimental data suggest that complex 1 intercalates into the DNA base pairs.
Upon irradiation, complex 1 was found to promote the cleavage of plasmid pBR 322 DNA from supercoiled form I to nicked form II.
The mechanism of the DNA cleavage by complex 1 was also investigated.
American Psychological Association (APA)
Mitsopoulou, Christiana A.& Dagas, Constantinos. 2010. Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with α-Diimine and Quinoxaline Ligands. Bioinorganic Chemistry and Applications،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-512696
Modern Language Association (MLA)
Mitsopoulou, Christiana A.& Dagas, Constantinos. Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with α-Diimine and Quinoxaline Ligands. Bioinorganic Chemistry and Applications No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-512696
American Medical Association (AMA)
Mitsopoulou, Christiana A.& Dagas, Constantinos. Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with α-Diimine and Quinoxaline Ligands. Bioinorganic Chemistry and Applications. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-512696
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512696