Clonal Hypereosinophilic Syndrome : Two Cases Report in Black Men from Sub-Saharan Africa and Literature Reviews
Joint Authors
Sallah, Levi kankoe
Vovor, Ahoefa
Segbena, Akuete Yvon
Messie, Kodjovi
Agbetiafa, Kossi
Kueviakoe, Irenee Messanh
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The first case is about a man of 60 years old suffering of hypereosinophilic syndrome (HES) developed since 1998.
He presented chronic cough, insomnia, and negative parasitical test.
We observed hypereosinophilia and fibroblastic hyperplasia at the bone marrow biopsy.
Initially, hydroxyurea and α-interferon treatment failed.
We proposed to him imatinib mesylate in May 2003.
The FIP1L1-PDGFRA gene was detected.
The second case is about a man of 34 years old seen in March 2002.
First investigation concluded to CML.
Progressively, eosinophil cells increased, and complications occurred as oedema syndrome, dyspnoea, and parietal chronic endocarditic fibrosis associated with pericarditis.
In addition, a bowel obstruction happened and was cured by surgery.
Bcr-abl fusion was negative, and FIP1L1-PDGFRA gene was detected after and imatinib mesylate was given.
Actually, endocarditic fibrosis decreased.
The two patients are in haematological and cytogenetic remission.
We concluded that clonal HES is present in Africa, and imatinib mesylate is effective.
American Psychological Association (APA)
Messie, Kodjovi& Vovor, Ahoefa& Kueviakoe, Irenee Messanh& Sallah, Levi kankoe& Agbetiafa, Kossi& Segbena, Akuete Yvon. 2011. Clonal Hypereosinophilic Syndrome : Two Cases Report in Black Men from Sub-Saharan Africa and Literature Reviews. ISRN Hematology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-512779
Modern Language Association (MLA)
Messie, Kodjovi…[et al.]. Clonal Hypereosinophilic Syndrome : Two Cases Report in Black Men from Sub-Saharan Africa and Literature Reviews. ISRN Hematology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-512779
American Medical Association (AMA)
Messie, Kodjovi& Vovor, Ahoefa& Kueviakoe, Irenee Messanh& Sallah, Levi kankoe& Agbetiafa, Kossi& Segbena, Akuete Yvon. Clonal Hypereosinophilic Syndrome : Two Cases Report in Black Men from Sub-Saharan Africa and Literature Reviews. ISRN Hematology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-512779
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512779