Blueberry Extracts Protect Testis from Hypobaric Hypoxia Induced Oxidative Stress in Rats
Joint Authors
Zepeda, Andrea
Aguayo, Luis G.
Acevedo, Alejandro
Calaf, Gloria M.
Figueroa, Carolina
Fuentealba, Jorge
Salgado, Perla
Farías, Jorge
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Exposure to hypobaric hypoxia causes oxidative damage to male rat reproductive function.
The aim of this study was to evaluate the protective effect of a blueberry extract (BB-4) in testis of rats exposed to hypobaric hypoxia.
Morphometric analysis, cellular DNA fragmentation, glutathione reductase (GR), and superoxide dismutase (SOD) activities were evaluated.
Our results showed that supplementation of BB-4 reduced lipid peroxidation, decreased apoptosis, and increased GR and SOD activities in rat testis under hypobaric hypoxia conditions (P<0.05).
Therefore, this study demonstrates that blueberry extract significantly reduced the harmful effects of oxidative stress caused by hypobaric hypoxia in rat testis by affecting glutathione reductase and superoxide dismutase activities.
American Psychological Association (APA)
Zepeda, Andrea& Aguayo, Luis G.& Fuentealba, Jorge& Figueroa, Carolina& Acevedo, Alejandro& Salgado, Perla…[et al.]. 2012. Blueberry Extracts Protect Testis from Hypobaric Hypoxia Induced Oxidative Stress in Rats. Oxidative Medicine and Cellular Longevity،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-512885
Modern Language Association (MLA)
Zepeda, Andrea…[et al.]. Blueberry Extracts Protect Testis from Hypobaric Hypoxia Induced Oxidative Stress in Rats. Oxidative Medicine and Cellular Longevity No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-512885
American Medical Association (AMA)
Zepeda, Andrea& Aguayo, Luis G.& Fuentealba, Jorge& Figueroa, Carolina& Acevedo, Alejandro& Salgado, Perla…[et al.]. Blueberry Extracts Protect Testis from Hypobaric Hypoxia Induced Oxidative Stress in Rats. Oxidative Medicine and Cellular Longevity. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-512885
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512885