Chiral Pharmaceutical Intermediaries Obtained by Reduction of 2-Halo-1-(4-substituted phenyl)-ethanones Mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182
Joint Authors
Rodrigues, J. Augusto R.
Moran, Paulo J. S.
Fardelone, Lucídio C.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Enantioselective reductions of p-R1-C6H4C(O)CH2R2 (R1 = Cl, Br, CH3, OCH3, NO2 and R2 = Br, Cl) mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182 afforded the corresponding halohydrins with complementary R and S configurations, respectively, in excellent yield and enantiomeric excesses.
The obtained (R)- or (S)-halohydrins are important building blocks in chemical and pharmaceutical industries.
American Psychological Association (APA)
Fardelone, Lucídio C.& Rodrigues, J. Augusto R.& Moran, Paulo J. S.. 2011. Chiral Pharmaceutical Intermediaries Obtained by Reduction of 2-Halo-1-(4-substituted phenyl)-ethanones Mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182. Enzyme Research،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-512929
Modern Language Association (MLA)
Fardelone, Lucídio C.…[et al.]. Chiral Pharmaceutical Intermediaries Obtained by Reduction of 2-Halo-1-(4-substituted phenyl)-ethanones Mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182. Enzyme Research No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-512929
American Medical Association (AMA)
Fardelone, Lucídio C.& Rodrigues, J. Augusto R.& Moran, Paulo J. S.. Chiral Pharmaceutical Intermediaries Obtained by Reduction of 2-Halo-1-(4-substituted phenyl)-ethanones Mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182. Enzyme Research. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-512929
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512929
