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Virtual Interactomics of Proteins from Biochemical Standpoint
Joint Authors
Souček, Pavel
Kubrycht, Jaroslav
Sigler, Karel
Source
Molecular Biology International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-08
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Virtual interactomics represents a rapidly developing scientific area on the boundary line of bioinformatics and interactomics.
Protein-related virtual interactomics then comprises instrumental tools for prediction, simulation, and networking of the majority of interactions important for structural and individual reproduction, differentiation, recognition, signaling, regulation, and metabolic pathways of cells and organisms.
Here, we describe the main areas of virtual protein interactomics, that is, structurally based comparative analysis and prediction of functionally important interacting sites, mimotope-assisted and combined epitope prediction, molecular (protein) docking studies, and investigation of protein interaction networks.
Detailed information about some interesting methodological approaches and online accessible programs or databases is displayed in our tables.
Considerable part of the text deals with the searches for common conserved or functionally convergent protein regions and subgraphs of conserved interaction networks, new outstanding trends and clinically interesting results.
In agreement with the presented data and relationships, virtual interactomic tools improve our scientific knowledge, help us to formulate working hypotheses, and they frequently also mediate variously important in silico simulations.
American Psychological Association (APA)
Kubrycht, Jaroslav& Sigler, Karel& Souček, Pavel. 2012. Virtual Interactomics of Proteins from Biochemical Standpoint. Molecular Biology International،Vol. 2012, no. 2012, pp.1-22.
https://search.emarefa.net/detail/BIM-512936
Modern Language Association (MLA)
Kubrycht, Jaroslav…[et al.]. Virtual Interactomics of Proteins from Biochemical Standpoint. Molecular Biology International No. 2012 (2012), pp.1-22.
https://search.emarefa.net/detail/BIM-512936
American Medical Association (AMA)
Kubrycht, Jaroslav& Sigler, Karel& Souček, Pavel. Virtual Interactomics of Proteins from Biochemical Standpoint. Molecular Biology International. 2012. Vol. 2012, no. 2012, pp.1-22.
https://search.emarefa.net/detail/BIM-512936
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512936