Date Fruit Extract Is a Neuroprotective Agent in Diabetic Peripheral Neuropathy in Streptozotocin-Induced Diabetic Rats : A Multimodal Analysis
Joint Authors
Zangiabadi, Nasser
Asadi, Ali Reza
Taj al-Din, Halah
Jafari, Mandana
Jarahi, Morteza
Sheibani, Vahid
Asadi-Shekaari, Majid
Shabani, Mohammad
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Background.
To study the effects of an aqueous extract of date fruit (Phoenix dactylifera L.
Arecaceae) diet on diabetic polyneuropathy (DPN) in streptozotocin- (STZ-) induced diabetic rats.
Methods.
The effects of a date fruit extract (DFE) diet on diabetic neuropathy in STZ-induced diabetic rats were evaluated and compared with a nondiabetic control group, diabetic control group (sham), and vehicle group with respect to the following parameters: open field behavioral test, motor nerve conduction velocity (MNCV), and morphological observations.
Results.
In the model of STZ-induced of diabetic neuropathy, chronic treatment for 6 weeks with DFE counteracted the impairment of the explorative activity of the rats in an open field behavioral test and of the conduction velocity of the sciatic nerve (MNCV).
In addition, pretreatment with DFE significantly reversed each nerve diameter reduction in diabetic rats.
Conclusion.
DFE treatment shows efficacy for preventing diabetic deterioration and for improving pathological parameters of diabetic neuropathy in rats, as compared with control groups.
American Psychological Association (APA)
Zangiabadi, Nasser& Asadi-Shekaari, Majid& Sheibani, Vahid& Jafari, Mandana& Shabani, Mohammad& Asadi, Ali Reza…[et al.]. 2011. Date Fruit Extract Is a Neuroprotective Agent in Diabetic Peripheral Neuropathy in Streptozotocin-Induced Diabetic Rats : A Multimodal Analysis. Oxidative Medicine and Cellular Longevity،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-512997
Modern Language Association (MLA)
Zangiabadi, Nasser…[et al.]. Date Fruit Extract Is a Neuroprotective Agent in Diabetic Peripheral Neuropathy in Streptozotocin-Induced Diabetic Rats : A Multimodal Analysis. Oxidative Medicine and Cellular Longevity No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-512997
American Medical Association (AMA)
Zangiabadi, Nasser& Asadi-Shekaari, Majid& Sheibani, Vahid& Jafari, Mandana& Shabani, Mohammad& Asadi, Ali Reza…[et al.]. Date Fruit Extract Is a Neuroprotective Agent in Diabetic Peripheral Neuropathy in Streptozotocin-Induced Diabetic Rats : A Multimodal Analysis. Oxidative Medicine and Cellular Longevity. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-512997
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512997