Biological Markers and Alzheimer Disease : A Canadian Perspective
Author
Source
International Journal of Alzheimer's Disease
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Decreased β-amyloid1-42 and increased phospho-tau protein levels in the cerebrospinal fluid (CSF) are currently the most accurate chemical neurodiagnostics of sporadic Alzheimer disease (AD).
A report (2007) of the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (2006) recommended that biological markers should not be currently requisitioned by primary care physicians in the routine investigation of subjects with memory complaints.
Consideration for such testing should prompt patient referral to a specialist engaged in dementia evaluations or a Memory Clinic.
The specialist should consider having CSF biomarkers (β-amyloid1-42 and phospho-tau) measured at a reputable facility in restricted cases presenting with atypical features and diagnostic confusion, but not as a routine procedure in all individuals with typical sporadic AD phenotypes.
We submit that developments in the field of AD biomarker discovery since publication of the 3rd CCCDTD consensus data do not warrant revision of the 2007 recommendations.
American Psychological Association (APA)
Schipper, Hyman M.. 2010. Biological Markers and Alzheimer Disease : A Canadian Perspective. International Journal of Alzheimer's Disease،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-513019
Modern Language Association (MLA)
Schipper, Hyman M.. Biological Markers and Alzheimer Disease : A Canadian Perspective. International Journal of Alzheimer's Disease No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-513019
American Medical Association (AMA)
Schipper, Hyman M.. Biological Markers and Alzheimer Disease : A Canadian Perspective. International Journal of Alzheimer's Disease. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-513019
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513019