Recent Advances in p53 Research and Cancer Treatment
Joint Authors
Suzuki, Kazufumi
Matsubara, Hisahiro
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
TP53, encoding p53, is one of the most famous tumor suppressor genes.
The majority of human cancers demonstrate the inactivation of the p53 pathway.
Mutant p53 not only, no longer, functions as a tumor suppressor but can also exert tumor-promoting effects.
The basic function of p53 is to respond to cellular stress.
We herein review the recent advances in p53 research and focus on apoptosis, cell cycle arrest, and senescence in response to stress.
We also review the clinical applications of p53-based therapy for human cancer.
American Psychological Association (APA)
Suzuki, Kazufumi& Matsubara, Hisahiro. 2011. Recent Advances in p53 Research and Cancer Treatment. Journal of Biomedicine and Biotechnology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-513028
Modern Language Association (MLA)
Suzuki, Kazufumi& Matsubara, Hisahiro. Recent Advances in p53 Research and Cancer Treatment. Journal of Biomedicine and Biotechnology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-513028
American Medical Association (AMA)
Suzuki, Kazufumi& Matsubara, Hisahiro. Recent Advances in p53 Research and Cancer Treatment. Journal of Biomedicine and Biotechnology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-513028
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513028