Specific Roles of MicroRNAs in Their Interactions with Environmental Factors
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
MicroRNAs (miRNAs) have emerged as critical regulators of gene expression by modulating numerous target mRNAs expression at posttranscriptional level.
Extensive studies have shown that miRNAs are critical in various important biological processes, including cell growth, proliferation, differentiation, development, and apoptosis.
In terms of their importance, miRNA dysfunction has been associated with a broad range of diseases.
Increased number of studies have shown that miRNAs can functionally interact with a wide spectrum of environmental factors (EFs) including drugs, industrial materials, virus and bacterial pathogens, cigarette smoking, alcohol, nutrition, sleep, exercise, stress, and radiation.
More importantly, the interactions between miRNAs and EFs have been shown to play critical roles in determining abnormal phenotypes and diseases.
In this paper, we propose an outline of the current knowledge about specific roles of miRNAs in their interactions with various EFs and analyze the literatures detailing miRNAs-EFs interactions in the context of various of diseases.
American Psychological Association (APA)
Wang, Juan& Cui, Qinghua. 2012. Specific Roles of MicroRNAs in Their Interactions with Environmental Factors. Journal of Nucleic Acids،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-513036
Modern Language Association (MLA)
Wang, Juan& Cui, Qinghua. Specific Roles of MicroRNAs in Their Interactions with Environmental Factors. Journal of Nucleic Acids No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-513036
American Medical Association (AMA)
Wang, Juan& Cui, Qinghua. Specific Roles of MicroRNAs in Their Interactions with Environmental Factors. Journal of Nucleic Acids. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-513036
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513036