Potential Explanatory Factors for Higher Incident Hip Fracture Risk in Older Diabetic Adults
Joint Authors
Fried, Linda F.
Siscovick, David S.
Harris, Tamara B.
Robbins, John A.
Strotmeyer, Elsa S.
Newman, Anne B.
Cauley, Jane A.
Kamineni, Aruna
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Type 2 diabetes is associated with higher fracture risk.
Diabetes-related conditions may account for this risk.
Cardiovascular Health Study participants (N=5641; 42.0% men; 15.5% black; 72.8±5.6 years) were followed 10.9 ± 4.6 years.
Diabetes was defined as hypoglycemic medication use or fasting glucose (FG) ≥126 mg/dL.
Peripheral artery disease (PAD) was defined as ankle-arm index <0.9.
Incident hip fractures were from medical records.
Crude hip fracture rates (/1000 person-years) were higher for diabetic vs.
non-diabetic participants with BMI <25 (13.6, 95% CI: 8.9–20.2 versus 11.4, 95% CI: 10.1–12.9) and BMI ≥25 to <30 (8.3, 95% CI: 5.7–11.9 versus 6.6, 95% CI: 5.6–7.7), but similar for BMI ≥30.
Adjusting for BMI, sex, race, and age, diabetes was related to fractures (HR = 1.34; 95% CI: 1.01–1.78).
PAD (HR = 1.25 (95% CI: 0.92–1.57)) and longer walk time (HR = 1.07 (95% CI: 1.04–1.10)) modified the fracture risk in diabetes (HR = 1.17 (95% CI: 0.87–1.57)).
Diabetes was associated with higher hip fracture risk after adjusting for BMI though this association was modified by diabetes-related conditions.
American Psychological Association (APA)
Strotmeyer, Elsa S.& Kamineni, Aruna& Cauley, Jane A.& Robbins, John A.& Fried, Linda F.& Siscovick, David S.…[et al.]. 2011. Potential Explanatory Factors for Higher Incident Hip Fracture Risk in Older Diabetic Adults. Current Gerontology and Geriatrics Research،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-513114
Modern Language Association (MLA)
Strotmeyer, Elsa S.…[et al.]. Potential Explanatory Factors for Higher Incident Hip Fracture Risk in Older Diabetic Adults. Current Gerontology and Geriatrics Research No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-513114
American Medical Association (AMA)
Strotmeyer, Elsa S.& Kamineni, Aruna& Cauley, Jane A.& Robbins, John A.& Fried, Linda F.& Siscovick, David S.…[et al.]. Potential Explanatory Factors for Higher Incident Hip Fracture Risk in Older Diabetic Adults. Current Gerontology and Geriatrics Research. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-513114
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513114