Protective Role of Melatonin in Neonatal Diseases

Joint Authors

D’Angelo, Gabriella
Marseglia, Lucia
Salpietro, Carmelo
Manti, Sara
Gitto, Eloisa
Barberi, Ignazio
Reiter, Russel J.

Source

Oxidative Medicine and Cellular Longevity

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-11-19

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Natural & Life Sciences (Multidisciplinary)
Biology

Abstract EN

Oxidative stress contributes to the severity of several newborn conditions to the extent that Saugstad coined the phrase “oxygen radical diseases of neonatology.” In order to counteract free radicals damage many strategies to augment antioxidant status in ill-term and preterm infants have been proposed and several medications have been experimented with mixed results.

Several studies have tested the efficacy of melatonin to counteract oxidative damage in diseases of newborns such as chronic lung disease, perinatal brain injury, necrotizing enterocolitis, and retinopathy of prematurity, giving promising results.

The peculiar perinatal susceptibility to oxidative stress indicates that prophylactic use of antioxidants as melatonin could help to prevent or at least reduce oxidative stress related diseases in newborns.

However, more studies are needed to confirm these beneficial effects.

American Psychological Association (APA)

Gitto, Eloisa& Marseglia, Lucia& Manti, Sara& D’Angelo, Gabriella& Barberi, Ignazio& Salpietro, Carmelo…[et al.]. 2013. Protective Role of Melatonin in Neonatal Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-513192

Modern Language Association (MLA)

Gitto, Eloisa…[et al.]. Protective Role of Melatonin in Neonatal Diseases. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-513192

American Medical Association (AMA)

Gitto, Eloisa& Marseglia, Lucia& Manti, Sara& D’Angelo, Gabriella& Barberi, Ignazio& Salpietro, Carmelo…[et al.]. Protective Role of Melatonin in Neonatal Diseases. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-513192

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-513192