Protective Role of Melatonin in Neonatal Diseases
Joint Authors
D’Angelo, Gabriella
Marseglia, Lucia
Salpietro, Carmelo
Manti, Sara
Gitto, Eloisa
Barberi, Ignazio
Reiter, Russel J.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Oxidative stress contributes to the severity of several newborn conditions to the extent that Saugstad coined the phrase “oxygen radical diseases of neonatology.” In order to counteract free radicals damage many strategies to augment antioxidant status in ill-term and preterm infants have been proposed and several medications have been experimented with mixed results.
Several studies have tested the efficacy of melatonin to counteract oxidative damage in diseases of newborns such as chronic lung disease, perinatal brain injury, necrotizing enterocolitis, and retinopathy of prematurity, giving promising results.
The peculiar perinatal susceptibility to oxidative stress indicates that prophylactic use of antioxidants as melatonin could help to prevent or at least reduce oxidative stress related diseases in newborns.
However, more studies are needed to confirm these beneficial effects.
American Psychological Association (APA)
Gitto, Eloisa& Marseglia, Lucia& Manti, Sara& D’Angelo, Gabriella& Barberi, Ignazio& Salpietro, Carmelo…[et al.]. 2013. Protective Role of Melatonin in Neonatal Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-513192
Modern Language Association (MLA)
Gitto, Eloisa…[et al.]. Protective Role of Melatonin in Neonatal Diseases. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-513192
American Medical Association (AMA)
Gitto, Eloisa& Marseglia, Lucia& Manti, Sara& D’Angelo, Gabriella& Barberi, Ignazio& Salpietro, Carmelo…[et al.]. Protective Role of Melatonin in Neonatal Diseases. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-513192
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513192