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Inhibition of Ceramide De Novo Synthesis with Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes
Joint Authors
Łukaszuk, Bartłomiej
Wiesiołek-Kurek, Patrycja
Kurek, Krzysztof
Chabowski, Adrian
Żendzian-Piotrowska, Małgorzata
Piotrowska, Dominika M.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Nowadays diabetes is one of the most common metabolic diseases.
Sphingolipids, which are vitally important constituents of intracellular signal transduction pathways, may be among the most pathogenic lipid moieties intermingled in the origin and development of diabetes.
It is now well established that inhibition of de novo ceramide synthesis with myriocin exerts positive effects on lipid metabolism and glucose homeostasis in type 2 diabetes mellitus animal models.
However, its influence on type I diabetes still remains unknown.
Therefore, the scope of this paper is to fulfill that particular gap in our knowledge.
American Psychological Association (APA)
Kurek, Krzysztof& Wiesiołek-Kurek, Patrycja& Piotrowska, Dominika M.& Łukaszuk, Bartłomiej& Chabowski, Adrian& Żendzian-Piotrowska, Małgorzata. 2014. Inhibition of Ceramide De Novo Synthesis with Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-513235
Modern Language Association (MLA)
Kurek, Krzysztof…[et al.]. Inhibition of Ceramide De Novo Synthesis with Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-513235
American Medical Association (AMA)
Kurek, Krzysztof& Wiesiołek-Kurek, Patrycja& Piotrowska, Dominika M.& Łukaszuk, Bartłomiej& Chabowski, Adrian& Żendzian-Piotrowska, Małgorzata. Inhibition of Ceramide De Novo Synthesis with Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-513235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513235