IVIG Effects on Erythrocyte Sedimentation Rate in Children
Joint Authors
Salehzadeh, Farhad
Jahangiri, Sepideh
Noshin, Ahmadvand
Source
International Journal of Pediatrics
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Erythrocyte sedimentation rate (ESR) is a valuable laboratory tool in evaluation of infectious, inflammatory, and malignant diseases.
Red blood cells in outside from the body precipitate due to their higher density than the plasma.
In this study we discuss the IVIG effect on ESR in different diseases and different ages.
Methods and Materials.
Fifty patients under 12 years old who had indication to receive IVIG enrolled in this study.
Total dose of IVIG was 2 gr/kg (400 mg/kg in five days or 2 gr/kg in single dose).
ESR before infusion of IVIG and within 24 hours after administration of the last dose of IVIG was checked.
Results.
23 (46%) patients were males and 27 (54%) were females.
The mean of ESR before IVIG was 31.8±29.04 and after IVIG it was 47.2±36.9; this difference was meaningful (P=0.05).
Results of ESR changes in different age groups, 6 patients less than 28 days, 13 patients from 1 month to 1 year, 20 patients from 1 to 6 years old, and 11 patients from 6 to 12 years have been meaningful (P=0.001, P=0.025, and P=0.006, resp.).
Conclusion.
In patients who are receiving IVIG as a therapy, ESR increased falsely (noninflammatory rising); therefore use of ESR for monitoring of response to treatment may be unreliable.
Although these results do not apply to neonatal group, we suggest that, in patients who received IVIG, interpretation of ESR should be used cautiously on followup.
American Psychological Association (APA)
Salehzadeh, Farhad& Noshin, Ahmadvand& Jahangiri, Sepideh. 2014. IVIG Effects on Erythrocyte Sedimentation Rate in Children. International Journal of Pediatrics،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-513299
Modern Language Association (MLA)
Salehzadeh, Farhad…[et al.]. IVIG Effects on Erythrocyte Sedimentation Rate in Children. International Journal of Pediatrics No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-513299
American Medical Association (AMA)
Salehzadeh, Farhad& Noshin, Ahmadvand& Jahangiri, Sepideh. IVIG Effects on Erythrocyte Sedimentation Rate in Children. International Journal of Pediatrics. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-513299
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513299