Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis
Joint Authors
Park, Ji-Yeun
Kim, Mi Hye
Kim, Seung-Nam
Yang, Woong Mo
Park, Hi-Joon
Choi, You Yeon
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Though the effects of acupuncture in atopic dermatitis have been proven in clinical studies, its mechanism remains unclear.
In this study, we investigate the effectiveness and mechanism of action for acupuncture treatment on the LI11 meridian point for treatment of allergic contact dermatitis.
BALB/c mice received 1-chloro-2,4-dinitrobenzene (DNCB) application to induce skin inflammation.
Acupuncture treatment on LI11 significantly inhibited cutaneous hyperplasia, serum IgE levels, and expression of proinflammatory cytokine (IL-4, IL-8, and TNF-α) mRNA and NF-κB, ERK1/2, JNK, and p38 proteins.
Acupuncture treatment of local points also inhibited cutaneous hyperplasia and serum IgE levels; however, it was not effective in regulating proinflammatory cytokines and proteins.
In addition, LI11 treatment is more effective at reducing serum IgE levels and pro-inflammatory cytokines and proteins than local point treatment.
These results suggest that acupuncture treatment is effective in alleviating allergic contact dermatitis by reducing pro-inflammatory cytokines and proteins.Erratum of “Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis”dx.doi.org/10.1155/2013/831539
American Psychological Association (APA)
Park, Ji-Yeun& Park, Hi-Joon& Choi, You Yeon& Kim, Mi Hye& Kim, Seung-Nam& Yang, Woong Mo. 2013. Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-513366
Modern Language Association (MLA)
Park, Ji-Yeun…[et al.]. Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-513366
American Medical Association (AMA)
Park, Ji-Yeun& Park, Hi-Joon& Choi, You Yeon& Kim, Mi Hye& Kim, Seung-Nam& Yang, Woong Mo. Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-513366
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513366