Expression of the Type VI Secretion System 1 Component Hcp1 Is Indirectly Repressed by OpaR in Vibrio parahaemolyticus
Joint Authors
Guo, Liping
Yan, Xiaojuan
Zhou, Dongsheng
Yang, Ruifu
Ma, Lizhi
Zhang, Yiquan
Wang, Li
Qiu, Jingfu
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
The type VI secretion system (T6SS) is bacterial protein injection machinery with roles in virulence, symbiosis, interbacterial interaction, antipathogenesis, and environmental stress responses.
There are two T6SS loci, T6SS1 and T6SS2, in the two chromosomes of Vibrio parahaemolyticus, respectively.
This work disclosed that the master quorum sensing (QS) regulator OpaR repressed the transcription of hcp1 encoding the structural component Hcp1 of T6SS1 in V.
parahaemolyticus, indicating that QS had a negative regulatory action on T6SS1.
A single σ54-dependent promoter was transcribed for hcp1 in V.
parahaemolyticus, and its activity was repressed by the OpaR regulator.
Since the OpaR protein could not bind to the upstream region of hcp1, OpaR would repress the transcription of hcp1 in an indirect manner.
American Psychological Association (APA)
Ma, Lizhi& Zhang, Yiquan& Yan, Xiaojuan& Guo, Liping& Wang, Li& Qiu, Jingfu…[et al.]. 2012. Expression of the Type VI Secretion System 1 Component Hcp1 Is Indirectly Repressed by OpaR in Vibrio parahaemolyticus. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-513369
Modern Language Association (MLA)
Ma, Lizhi…[et al.]. Expression of the Type VI Secretion System 1 Component Hcp1 Is Indirectly Repressed by OpaR in Vibrio parahaemolyticus. The Scientific World Journal No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-513369
American Medical Association (AMA)
Ma, Lizhi& Zhang, Yiquan& Yan, Xiaojuan& Guo, Liping& Wang, Li& Qiu, Jingfu…[et al.]. Expression of the Type VI Secretion System 1 Component Hcp1 Is Indirectly Repressed by OpaR in Vibrio parahaemolyticus. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-513369
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513369