Zhen Gan Xi Feng Decoction, a Traditional Chinese Herbal Formula, for the Treatment of Essential Hypertension : A Systematic Review of Randomized Controlled Trials
Joint Authors
Liu, Wei
Chu, Fuyong
Li, Haixia
Wang, Pengqian
Duan, Lian
Wang, Jie
Du, Xinliang
Yang, Xiaochen
Li, Xiaoke
Zhang, Guohao
Li, Nan
Feng, Bo
Ma, Jizheng
Xiong, Xingjiang
Su, Kelei
Gao, Ao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
To assess the clinical effectiveness and adverse effects of Zhen Gan Xi Feng Decoction (ZGXFD) for essential hypertension (EH).
Methods.
Five major electronic databases were searched up to August 2012 to retrieve any potential randomized controlled trials designed to evaluate the clinical effectiveness of ZGXFD for EH reported in any language, with main outcome measure as blood pressure (BP).
Results.
Six randomized trials were included.
Methodological quality of the trials was evaluated as generally low.
Four trials compared prescriptions based on ZGXFD with antihypertensive drugs.
Meta-analysis showed that ZGXFD was more effective in BP control and TCM syndrome and symptom differentiation (TCM-SSD) scores than antihypertensive drugs.
Two trials compared the combination of modified ZGXFD plus antihypertensive drugs with antihypertensive drugs.
Meta-analysis showed that there is significant beneficial effect on TCM-SSD scores.
However, no significant effect on BP was found.
The safety of ZGXFD is still uncertain.
Conclusions.
ZGXFD appears to be effective in improving blood pressure and hypertension-related symptoms for EH.
However, the evidence remains weak due to poor methodological quality of the included studies.
More rigorous trials are warranted to support their clinical use.
American Psychological Association (APA)
Xiong, Xingjiang& Yang, Xiaochen& Feng, Bo& Liu, Wei& Duan, Lian& Gao, Ao…[et al.]. 2013. Zhen Gan Xi Feng Decoction, a Traditional Chinese Herbal Formula, for the Treatment of Essential Hypertension : A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-513388
Modern Language Association (MLA)
Xiong, Xingjiang…[et al.]. Zhen Gan Xi Feng Decoction, a Traditional Chinese Herbal Formula, for the Treatment of Essential Hypertension : A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-513388
American Medical Association (AMA)
Xiong, Xingjiang& Yang, Xiaochen& Feng, Bo& Liu, Wei& Duan, Lian& Gao, Ao…[et al.]. Zhen Gan Xi Feng Decoction, a Traditional Chinese Herbal Formula, for the Treatment of Essential Hypertension : A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-513388
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513388