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Autoantibodies to Tailor-Made Panels of Tumor-Associated Antigens in Breast Carcinoma
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Autoantibodies (AAbs) to tumor-associated antigens (TAAs) have been identified in the sera of cancer patients.
In a previous review published in this journal, we have focused on recent knowledge related to circulating AAbs to individual TAAs in breast carcinoma.
This review will focus on recent knowledge related to AAb assays to tailor-made panels of TAAs in breast carcinoma.
So far, AAb assays to the following tailor-made panels of TAAs have been assessed in breast carcinoma: (1) p53, c-myc, HER2, NY-ESO-1, BRCA2, and MUC1, (2) IMP1, p62, Koc, p53, c-MYC, cyclin B1, and survivin, (3) PPIA, PRDX2, FKBP52, HSP-60, and MUC1, (4) MUC1, HER2, p53, and IGFBP2, (5) p53, HER2, IGFBP-2, and TOPO2α, (6) survivin and livin, (7) ASB-9, SERAC1, and RELT, and (8) p16, p53, and c-myc.
Assessment of serum AAbs to a tailor-made panel of TAAs provides better sensitivity to diagnosis of breast carcinoma than measuring serum AAbs to a single TAA.
Nevertheless, measurement of serum AAbs to a panel of TAAs for screening and early diagnosis of breast carcinoma is still investigational and should be carried out along with traditional diagnostic studies.
American Psychological Association (APA)
Piura, Ettie& Piura, Benjamin. 2011. Autoantibodies to Tailor-Made Panels of Tumor-Associated Antigens in Breast Carcinoma. Journal of Oncology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-513395
Modern Language Association (MLA)
Piura, Ettie& Piura, Benjamin. Autoantibodies to Tailor-Made Panels of Tumor-Associated Antigens in Breast Carcinoma. Journal of Oncology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-513395
American Medical Association (AMA)
Piura, Ettie& Piura, Benjamin. Autoantibodies to Tailor-Made Panels of Tumor-Associated Antigens in Breast Carcinoma. Journal of Oncology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-513395
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513395