Construction of a Drug Safety Assurance Information System Based on Clinical Genotyping
Joint Authors
Kane, Michael D.
Iannotti, Nicholas V.
Sprague, Jon E.
Springer, John A.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
To capitalize on the vast potential of patient genetic information to aid in assuring drug safety, a substantial effort is needed in both the training of healthcare professionals and the operational enablement of clinical environments.
Our research aims to satisfy these needs through the development of a drug safety assurance information system (GeneScription) based on clinical genotyping that utilizes patient-specific genetic information to predict and prevent adverse drug responses.
In this paper, we present the motivations for this work, the algorithms at the heart of GeneScription, and a discussion of our system and its uses.
We also describe our efforts to validate GeneScription through its evaluation by practicing pharmacists and pharmacy professors and its repeated use in training pharmacists.
The positive assessment of the GeneScription software tool by these domain experts provides strong validation of the importance, accuracy, and effectiveness of GeneScription.
American Psychological Association (APA)
Springer, John A.& Iannotti, Nicholas V.& Sprague, Jon E.& Kane, Michael D.. 2011. Construction of a Drug Safety Assurance Information System Based on Clinical Genotyping. ISRN Bioinformatics،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-513422
Modern Language Association (MLA)
Springer, John A.…[et al.]. Construction of a Drug Safety Assurance Information System Based on Clinical Genotyping. ISRN Bioinformatics No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-513422
American Medical Association (AMA)
Springer, John A.& Iannotti, Nicholas V.& Sprague, Jon E.& Kane, Michael D.. Construction of a Drug Safety Assurance Information System Based on Clinical Genotyping. ISRN Bioinformatics. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-513422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513422