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Sense and Nonsense of an Extended Pelvic Lymph Node Dissection in Prostate Cancer
Joint Authors
Briganti, Alberto
Mottet, Nicolas
Van Baelen, Anthony
Joniau, Steven
Gontero, Paolo
Spahn, Martin
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Lymph node metastases associated with prostate cancer (PCa) has been shown to be a poor prognostic factor.
The role of pelvic lymph node dissection (PLND) itself in relation to survival remains unclear, however.
A Medline search was conducted to address this issue.
The following conclusions were drawn.
Only recently, improved survival due to completion of radical prostatectomy (RP) (compared to abandoning RP) in known or presumed lymph-node-positive patients has been shown.
Lymph node sampling can only be considered representative if an adequate number of nodes is removed.
While several authors have suggested that a therapeutic benefit in patients undergoing RP is not provided by PLND, the reliability of these studies is uncertain.
Contrary to this, several studies have indicated the possibility of long-term survival even in the presence of limited lymph node metastases.
The role and timing of initiation of adjuvant androgen deprivation therapy (ADT) in patients who have node-positive disease after RP is controversial.
Recent studies suggest that delaying ADT may not adversely impact survival.
American Psychological Association (APA)
Van Baelen, Anthony& Mottet, Nicolas& Spahn, Martin& Briganti, Alberto& Gontero, Paolo& Joniau, Steven. 2011. Sense and Nonsense of an Extended Pelvic Lymph Node Dissection in Prostate Cancer. Advances in Urology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-513450
Modern Language Association (MLA)
Van Baelen, Anthony…[et al.]. Sense and Nonsense of an Extended Pelvic Lymph Node Dissection in Prostate Cancer. Advances in Urology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-513450
American Medical Association (AMA)
Van Baelen, Anthony& Mottet, Nicolas& Spahn, Martin& Briganti, Alberto& Gontero, Paolo& Joniau, Steven. Sense and Nonsense of an Extended Pelvic Lymph Node Dissection in Prostate Cancer. Advances in Urology. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-513450
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513450