Ectopic Fat and Insulin Resistance : Pathophysiology and Effect of Diet and Lifestyle Interventions
Joint Authors
Smit, J. W. A.
Schoones, J.
Snel, M.
Jazet, I. M.
Pijl, Hanno
Jonker, J. T.
Lamb, H.
Meinders, A. E.
de Roos, A.
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-24
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
The storage of triglyceride (TG) droplets in nonadipose tissues is called ectopic fat storage.
Ectopic fat is associated with insulin resistance and type 2 diabetes mellitus (T2DM).
Not the triglycerides per se but the accumulation of intermediates of lipid metabolism in organs, such as the liver, skeletal muscle, and heart seem to disrupt metabolic processes and impair organ function.
We describe the mechanisms of ectopic fat depositions in the liver, skeletal muscle, and in and around the heart and the consequences for each organs function.
In addition, we systematically reviewed the literature for the effects of diet-induced weight loss and exercise on ectopic fat depositions.
American Psychological Association (APA)
Snel, M.& Jonker, J. T.& Schoones, J.& Lamb, H.& de Roos, A.& Pijl, Hanno…[et al.]. 2012. Ectopic Fat and Insulin Resistance : Pathophysiology and Effect of Diet and Lifestyle Interventions. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-513525
Modern Language Association (MLA)
Snel, M.…[et al.]. Ectopic Fat and Insulin Resistance : Pathophysiology and Effect of Diet and Lifestyle Interventions. International Journal of Endocrinology No. 2012 (2012), pp.1-18.
https://search.emarefa.net/detail/BIM-513525
American Medical Association (AMA)
Snel, M.& Jonker, J. T.& Schoones, J.& Lamb, H.& de Roos, A.& Pijl, Hanno…[et al.]. Ectopic Fat and Insulin Resistance : Pathophysiology and Effect of Diet and Lifestyle Interventions. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-513525
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513525