Risk Factors for Dysmotility, Acid Reflux Symptoms, and Overlap Using FSSG in Japan

Abstract EN

Aims.

FSSG {frequency scale for the symptoms of gastroesophageal reflux disease (GERD)} was developed as a diagnostic tool for dysmotility and acid reflux symptoms.

We first used FSSG to investigate the prevalence and risk factors for dysmotility and acid reflux symptoms and overlap of the two symptoms in a Japanese population.

Methods.

A cross-sectional survey was performed in Japanese underwent the routine medical examination.

Dysmotility and acid reflux symptom were diagnosed by using FSSG.

Subjects met both criteria were considered as overlap group.

Results.

Among 778 subjects, 395 persons were included in the final analyses.

Dysmotility symptoms were found in 32.6% and acid reflux symptoms in 20.5%.

Their overlap was found in 13.9% of all 395 subjects, which in 42.6% of dysmotility symptoms and 67.9% of acid reflux symptoms.

Multiple logistic analysis showed that female gender was significantly associated with dysmotility symptoms compared with controls.

Female gender, smoking, and hiatus hernia were significantly associated with overlap.

Smoking was significantly associated with overlap compared with dysmotility symptoms alone and acid reflux symptoms alone.

Conclusions.

Overlap between dysmotility and acid reflux symptoms was common in Japan.

Smoking was an independent risk factor for overlap among two symptoms.