Hemozoin Inhibition and Control of Clinical Malaria
Joint Authors
Nwanegbo, Edward Chieke
Esimone, Charles Okechukwu
Ihekwereme, Chibueze Peter
Source
Advances in Pharmacological Sciences
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Malaria has a negative impact on health and social and economic life of residents of endemic countries.
The ultimate goals of designing new treatment for malaria are to prevent clinical infection, reduce morbidity, and decrease mortality.
There are great advances in the understanding of the parasite-host interaction through studies by various scientists.
In some of these studies, attempts were made to evaluate the roles of malaria pigment or toxins in the pathogenesis of malaria.
Hemozoin is a key metabolite associated with severe malaria anemia (SMA), immunosuppression, and cytokine dysfunction.
Targeting of this pigment may be necessary in the design of new therapeutic products against malaria.
In this review, the roles of hemozoin in the morbidity and mortality of malaria are highlighted as an essential target in the quest for effective control of clinical malaria.
American Psychological Association (APA)
Ihekwereme, Chibueze Peter& Esimone, Charles Okechukwu& Nwanegbo, Edward Chieke. 2014. Hemozoin Inhibition and Control of Clinical Malaria. Advances in Pharmacological Sciences،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-513562
Modern Language Association (MLA)
Ihekwereme, Chibueze Peter…[et al.]. Hemozoin Inhibition and Control of Clinical Malaria. Advances in Pharmacological Sciences No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-513562
American Medical Association (AMA)
Ihekwereme, Chibueze Peter& Esimone, Charles Okechukwu& Nwanegbo, Edward Chieke. Hemozoin Inhibition and Control of Clinical Malaria. Advances in Pharmacological Sciences. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-513562
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513562