Synthesis and In Vitro Cytotoxic Activity of Chromenopyridones
Joint Authors
Ishar, Mohan Paul Singh
Singh, Gagandeep
Kumar, Rakesh
Sharma, Vishal
Singh, Balwinder
Arora, Saroj
Source
International Journal of Medicinal Chemistry
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Novel substituted chromenopyridones (3a–j and 6a–d) were synthesized and evaluated in vitro for the cytotoxic activity against various human cancer cell lines such as prostate (PC-3), breast (MCF-7), CNS (IMR-32), cervix (Hela), and liver (Hep-G2).
preliminary cytotoxic screening showed that all the compounds possess a good to moderate inhibitory activity against various cancer cell lines.
Particularly, compound 6b bearing allyl moiety displayed a significant cytotoxic potential in comparison to standard drugs.
American Psychological Association (APA)
Singh, Balwinder& Sharma, Vishal& Singh, Gagandeep& Kumar, Rakesh& Arora, Saroj& Ishar, Mohan Paul Singh. 2013. Synthesis and In Vitro Cytotoxic Activity of Chromenopyridones. International Journal of Medicinal Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-513586
Modern Language Association (MLA)
Singh, Balwinder…[et al.]. Synthesis and In Vitro Cytotoxic Activity of Chromenopyridones. International Journal of Medicinal Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-513586
American Medical Association (AMA)
Singh, Balwinder& Sharma, Vishal& Singh, Gagandeep& Kumar, Rakesh& Arora, Saroj& Ishar, Mohan Paul Singh. Synthesis and In Vitro Cytotoxic Activity of Chromenopyridones. International Journal of Medicinal Chemistry. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-513586
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513586
