Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue

Joint Authors

Jonges, G. N.
Witteveen, P. O.
Homs, M. Y. V.
Schreuder, H. W. R.

Source

Case Reports in Obstetrics and Gynecology

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-10-07

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Malignant ovarian germ cell tumor is a rare disease, but with current treatment strategies including surgery and platinum based chemotherapy survival is excellent.

After treatment, intensive followup is indicated to encounter tumor relapse at an early stage.

This case describes a 22-year-old female with a history of common variable immune deficiency (CVID) who underwent a resection of a large ovarian germ cell tumor followed by 4 cycles of cisplatin and etoposide resulting in clinical complete remission.

During followup, she developed a mass at the umbilicus and ascites.

Initially, the cytology of the ascites was interpreted as tumor positive, suspicious of relapse of the disease, but tumor markers remained negative.

However, during laparoscopy it turned out to be a mature teratoma, which can develop after chemotherapy, the so called growing teratoma syndrome.

In retrospect, the ascites was false positive.

This case shows that current diagnostic tools are not sufficient to distinguish between vital tumor and mature teratoma and can be misleading.

Tumor biopsy and/or laparoscopic inspection are therefore indicated.

American Psychological Association (APA)

Homs, M. Y. V.& Schreuder, H. W. R.& Jonges, G. N.& Witteveen, P. O.. 2013. Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue. Case Reports in Obstetrics and Gynecology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-513605

Modern Language Association (MLA)

Homs, M. Y. V.…[et al.]. Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue. Case Reports in Obstetrics and Gynecology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-513605

American Medical Association (AMA)

Homs, M. Y. V.& Schreuder, H. W. R.& Jonges, G. N.& Witteveen, P. O.. Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue. Case Reports in Obstetrics and Gynecology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-513605

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-513605