Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue
Joint Authors
Jonges, G. N.
Witteveen, P. O.
Homs, M. Y. V.
Schreuder, H. W. R.
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Malignant ovarian germ cell tumor is a rare disease, but with current treatment strategies including surgery and platinum based chemotherapy survival is excellent.
After treatment, intensive followup is indicated to encounter tumor relapse at an early stage.
This case describes a 22-year-old female with a history of common variable immune deficiency (CVID) who underwent a resection of a large ovarian germ cell tumor followed by 4 cycles of cisplatin and etoposide resulting in clinical complete remission.
During followup, she developed a mass at the umbilicus and ascites.
Initially, the cytology of the ascites was interpreted as tumor positive, suspicious of relapse of the disease, but tumor markers remained negative.
However, during laparoscopy it turned out to be a mature teratoma, which can develop after chemotherapy, the so called growing teratoma syndrome.
In retrospect, the ascites was false positive.
This case shows that current diagnostic tools are not sufficient to distinguish between vital tumor and mature teratoma and can be misleading.
Tumor biopsy and/or laparoscopic inspection are therefore indicated.
American Psychological Association (APA)
Homs, M. Y. V.& Schreuder, H. W. R.& Jonges, G. N.& Witteveen, P. O.. 2013. Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue. Case Reports in Obstetrics and Gynecology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-513605
Modern Language Association (MLA)
Homs, M. Y. V.…[et al.]. Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue. Case Reports in Obstetrics and Gynecology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-513605
American Medical Association (AMA)
Homs, M. Y. V.& Schreuder, H. W. R.& Jonges, G. N.& Witteveen, P. O.. Clinical and Radiologic Signs of Relapsed Ovarian Germ Cell Tumor : Tissue Is the Issue. Case Reports in Obstetrics and Gynecology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-513605
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513605