Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer
Joint Authors
Cabanillas, Maria E.
Hu, Mimi I.
Durand, Jean-Bernard
Busaidy, Naifa Lamki
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Tyrosine kinase inhibitors (TKIs) which target angiogenesis are promising treatments for patients with metastatic medullary and differentiated thyroid cancers.
Sorafenib, sunitinib, and pazopanib are commercially available drugs which have been studied in these diseases.
Vandetanib is the first drug approved in the United States for treatment of medullary thyroid cancer.
These TKIs are used as chronic therapies, and therefore it is imperative to understand the adverse event profile in order to avoid excessive toxicity and maintain patients on therapy as long as it proves beneficial.
Here we review common toxicities, management of these, and other challenging situations that arise when using TKIs in patients with thyroid cancer.
American Psychological Association (APA)
Cabanillas, Maria E.& Hu, Mimi I.& Durand, Jean-Bernard& Busaidy, Naifa Lamki. 2011. Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer. Journal of Thyroid Research،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-513740
Modern Language Association (MLA)
Cabanillas, Maria E.…[et al.]. Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer. Journal of Thyroid Research No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-513740
American Medical Association (AMA)
Cabanillas, Maria E.& Hu, Mimi I.& Durand, Jean-Bernard& Busaidy, Naifa Lamki. Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer. Journal of Thyroid Research. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-513740
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513740