Assessment of Platelet Indices in Patients with Neurodegenerative Diseases : Mean Platelet Volume Was Increased in Patients with Parkinson’s Disease
Joint Authors
Koçer, Emel
Koçer, Abdulkadir
Dürüyen, Hümeyra
Yaman, Aslı
Niftaliyev, Elvin
Eryılmaz, Mehmet
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Platelets induce chronic inflammation which is a key step in atherosclerosis and may be involved in the progression of neurodegenerative diseases (NDD).
We aimed to measure the mean platelet volume (MPV) and platelet count (PLC) in NDD patients.
The present study was designed to investigate the platelet function by measuring MPV and PLC in NDD.
A total of 182 outpatients with Alzheimer’s (AD) or Parkinson’s diseases (PD) were included.
The control group consisted of 104 healthy subjects.
Platelet count was similar between groups.
MPV values of PD patients were higher than those of AD patients and controls (P<0.001).
MPV correlated negatively with Heohn and Yahr scale (HYS) score (P<0.001).
Increased MPV in patients with PD may point to a platelet dysfunction.
High-grade inflammation presents with low levels of MPV as seen in PD patients with high HYS scores.
American Psychological Association (APA)
Koçer, Abdulkadir& Yaman, Aslı& Niftaliyev, Elvin& Dürüyen, Hümeyra& Eryılmaz, Mehmet& Koçer, Emel. 2013. Assessment of Platelet Indices in Patients with Neurodegenerative Diseases : Mean Platelet Volume Was Increased in Patients with Parkinson’s Disease. Current Gerontology and Geriatrics Research،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-513788
Modern Language Association (MLA)
Koçer, Abdulkadir…[et al.]. Assessment of Platelet Indices in Patients with Neurodegenerative Diseases : Mean Platelet Volume Was Increased in Patients with Parkinson’s Disease. Current Gerontology and Geriatrics Research No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-513788
American Medical Association (AMA)
Koçer, Abdulkadir& Yaman, Aslı& Niftaliyev, Elvin& Dürüyen, Hümeyra& Eryılmaz, Mehmet& Koçer, Emel. Assessment of Platelet Indices in Patients with Neurodegenerative Diseases : Mean Platelet Volume Was Increased in Patients with Parkinson’s Disease. Current Gerontology and Geriatrics Research. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-513788
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513788