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Leigh's Disease : The Acute Clinical Course of a Two-Year-Old Child with Subacute Necrotizing Encephalomyelopathy
Joint Authors
Buettner, Andreas
Zinka, Bettina
Graw, Matthias
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-10
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We report the untypical clinical course of a previously healthy two-year-old girl, who died suddenly and unexpectedly after an episode of vomiting.
At forensic autopsy no other pathological findings could be diagnosed than multiple reddish, sunken areas in brain stem, mesencephalon, and pons.
Histologically they presented as areas of spongiosis of the neuropil with prominent endothelial hyperplasia and vascular proliferation whereas nerve cells were well preserved.
On the basis of the characteristic neuropathological findings in combination with the age of the child, we had to take into consideration that the child might have died from subacute necrotizing encephalomyelopathy (Leigh's Disease) despite the untypical, fulminant clinical course.
American Psychological Association (APA)
Zinka, Bettina& Buettner, Andreas& Graw, Matthias. 2010. Leigh's Disease : The Acute Clinical Course of a Two-Year-Old Child with Subacute Necrotizing Encephalomyelopathy. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-513791
Modern Language Association (MLA)
Zinka, Bettina…[et al.]. Leigh's Disease : The Acute Clinical Course of a Two-Year-Old Child with Subacute Necrotizing Encephalomyelopathy. Case Reports in Medicine No. 2010 (2010), pp.1-3.
https://search.emarefa.net/detail/BIM-513791
American Medical Association (AMA)
Zinka, Bettina& Buettner, Andreas& Graw, Matthias. Leigh's Disease : The Acute Clinical Course of a Two-Year-Old Child with Subacute Necrotizing Encephalomyelopathy. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-513791
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513791