Th17 Cells in Immunity and Autoimmunity
Joint Authors
Larkin, Joseph
Bedoya, Simone Kennedy
Lam, Brandon
Lau, Kenneth
Source
Clinical and Developmental Immunology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-26
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Th17 and IL-17 play important roles in the clearance of extracellular bacterial and fungal infections.
However, strong evidence also implicates the Th17 lineage in several autoimmune disorders including multiple sclerosis, psoriasis, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and asthma.
The Th17 subset has also been connected with type I diabetes, although whether it plays a role in the pathogenicity of or protection from the disease remains a controversial issue.
In this review we have provided a comprehensive overview of Th17 pathogenicity and function, including novel evidence for a protective role of Th17 cells in conjunction with the microbiota gut flora in T1D onset and progression.
American Psychological Association (APA)
Bedoya, Simone Kennedy& Lam, Brandon& Lau, Kenneth& Larkin, Joseph. 2013. Th17 Cells in Immunity and Autoimmunity. Clinical and Developmental Immunology،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-513839
Modern Language Association (MLA)
Bedoya, Simone Kennedy…[et al.]. Th17 Cells in Immunity and Autoimmunity. Clinical and Developmental Immunology No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-513839
American Medical Association (AMA)
Bedoya, Simone Kennedy& Lam, Brandon& Lau, Kenneth& Larkin, Joseph. Th17 Cells in Immunity and Autoimmunity. Clinical and Developmental Immunology. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-513839
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513839