Postsurgical Pathologies Associated with Intradural Electrical Stimulation in the Central Nervous System : Design Implications for a New Clinical Device
Joint Authors
Oya, Hiroyuki
Gillies, George T.
Gibson-Corley, Katherine N.
Howard, Matthew A.
Flouty, Oliver
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Spinal cord stimulation has been utilized for decades in the treatment of numerous conditions such as failed back surgery and phantom limb syndromes, arachnoiditis, cancer pain, and others.
The placement of the stimulating electrode array was originally subdural but, to minimize surgical complexity and reduce the risk of certain postsurgical complications, it became exclusively epidural eventually.
Here we review the relevant clinical and experimental pathologic findings, including spinal cord compression, infection, hematoma formation, cerebrospinal fluid leakage, chronic fibrosis, and stimulation-induced neurotoxicity, associated with the early approaches to subdural electrical stimulation of the central nervous system, and the spinal cord in particular.
These findings may help optimize the safety and efficacy of a new approach to subdural spinal cord stimulation now under development.
American Psychological Association (APA)
Gibson-Corley, Katherine N.& Flouty, Oliver& Oya, Hiroyuki& Gillies, George T.& Howard, Matthew A.. 2014. Postsurgical Pathologies Associated with Intradural Electrical Stimulation in the Central Nervous System : Design Implications for a New Clinical Device. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-513973
Modern Language Association (MLA)
Gibson-Corley, Katherine N.…[et al.]. Postsurgical Pathologies Associated with Intradural Electrical Stimulation in the Central Nervous System : Design Implications for a New Clinical Device. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-513973
American Medical Association (AMA)
Gibson-Corley, Katherine N.& Flouty, Oliver& Oya, Hiroyuki& Gillies, George T.& Howard, Matthew A.. Postsurgical Pathologies Associated with Intradural Electrical Stimulation in the Central Nervous System : Design Implications for a New Clinical Device. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-513973
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-513973