The Role of Chlamydia trachomatis Polymorphic Membrane Proteins in Inflammation and Sequelae among Women with Pelvic Inflammatory Disease
Joint Authors
Bavoil, Patrik M.
Haggerty, Catherine L.
Tan, Chun
Ness, Roberta B.
Darville, Toni
Taylor, Brandie D.
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Chlamydia trachomatis polymorphic membrane proteins (Pmps) may increase genital tract inflammation and play a role in virulence.
Antibody levels for PmpA, PmpD, and PmpI, measured in densitometric units, were assessed among a pilot sample of 40 C.
trachomatis-infected women with mild-to-moderate clinical PID.
Women who expressed antibodies to PmpA were less likely to achieve pregnancy (40.0% versus 85.7%; P=0.042) and less likely to have a live birth (0.0% versus 80.0%; P=0.005) compared to women who did not express antibody to PmpA.
Women who expressed antibodies to PmpI were more likely to have upper genital tract infection (61.5% versus 20.0%; P=0.026).
However, seropositivity to PmpI and PmpD did not modify the risk of reproductive sequelae or inflammation.
Seropositivity to chlamydial PmpA may represent a biomarker of increased risk of sequelae secondary to infection with C.
trachomatis.
American Psychological Association (APA)
Taylor, Brandie D.& Darville, Toni& Tan, Chun& Bavoil, Patrik M.& Ness, Roberta B.& Haggerty, Catherine L.. 2011. The Role of Chlamydia trachomatis Polymorphic Membrane Proteins in Inflammation and Sequelae among Women with Pelvic Inflammatory Disease. Infectious Diseases in Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-514029
Modern Language Association (MLA)
Taylor, Brandie D.…[et al.]. The Role of Chlamydia trachomatis Polymorphic Membrane Proteins in Inflammation and Sequelae among Women with Pelvic Inflammatory Disease. Infectious Diseases in Obstetrics and Gynecology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-514029
American Medical Association (AMA)
Taylor, Brandie D.& Darville, Toni& Tan, Chun& Bavoil, Patrik M.& Ness, Roberta B.& Haggerty, Catherine L.. The Role of Chlamydia trachomatis Polymorphic Membrane Proteins in Inflammation and Sequelae among Women with Pelvic Inflammatory Disease. Infectious Diseases in Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-514029
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-514029