Extra-ovarian granulosa cell tumor : a case report

Abstract EN

Extraovarian granulosa cell tumor is a very rare tumor, assumed to arise from mesenchymal tissue along the embryonal route of the genital ridge.

One such rare case of extraovarian granulosa cell tumor was encountered in a 73-year-old female patient who presented with a large intraabdominal mass.

Computerized tomography revealed a large retroperitoneal mass measuring 9 cm x 6.5 cm.

Her past medical history was irrelevant.

She underwent exploration laparotomy and the mass was excised.

Histopathological examination of the excised mass showed features of adult-type granulosa cell tumor.

Because metastatic epithelial tumors, particularly from the ovaries, may show identical morphology, immunostains for inhibin and Epithelial Membrane Antigen (EMA) were performed.

The tumor showed positivity for inhibin while epithelial membrane antigen was negative thus confirming the diagnosis of granulosa cell tumor.

A diagnosis of extraovarian granulosa cell tumor can only be done after excluding any previous history of granulosa cell tumor of the ovary.

Immunostains help to differentiate granulosa cell tumors from other neoplasms.