Preeclampsia : the effect of iiitravenous fluid preload on vasoactive peptide secretion during caesarean section under spinal anaesthesia
Other Title(s)
تأثير إعطاء المحاليل الوريدية المسبقة على إفراز البروتينات القابضة للأوعية الدموية أثناء إجراء جراحة العمليات القيصرية لمرضى تسمم الحمل تحت تأثير التخدير النصفي
Joint Authors
Abd al-Al, Fatimah Ahmad
Makki, Abd al-Rahim Muhammad Abd al-Hafiz
al-Muraba, Hani Ahmad Ibrahim
Fathi, Julnar Muhammad
Sayyid, Jihan Ahmad
Abd al-Al, Diya al-Din Muhammad
Source
Issue
Vol. 29, Issue 2 (31 May. 2005), pp.109-124, 16 p.
Publisher
Assiut University Faculty of Medicine
Publication Date
2005-05-31
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Topics
Abstract EN
We followed the haemodynamic parameters and determined the peripheral venous levels of ANP, ET-1 and NO before and after intravenous volume preload of 1 litre Ringer's solution, followed by a further load of the same volume under spinal anaesthesia in 15 healthy and 15 pre-eclamptic women.
Blood pressure was decreased significantly in both groups after spinal anaesthesia and such decrease was less in the preeclamptic group.
The baseline concentration of ANP was higher in preeclamptic women than in normal pregnancy women It increased significantly in both groups after the 1st infusion, the 2" infusion and after delivery.
The CVP increased more during the preload ^period in the preeclamptic group than in healthy women The increase in the concentrations of ANP correlated significantly with the increase in CVP in total study group.
The baseline concentration of ET-1 was higher in preeclamptic women than in healthy women.
It decreased significantly in both groups after the first and second infusions.
The plasma concentrations of ET-1 increased significantly in the cord sample in both groups.
NO increased more in the preeclamptic group during the preload period than in healthy women while the same increase was noted after the second infusion in both groups.
After delivery NO concentration in the cord sample was higher in the preeclamptic group than in healthy women.
There was no significant difference in the number of neonates with Apgar score <7, NACS and the parameters of arterial blood gas between the two groups.
We conclude from this study that the release of ANP increases in response to a rapid intravenous infusion of a crystalloid solution during elective Caesarean delivery which is exaggerated in women with preeclampsia.
This may help in the vasculatory adaptation to the volume load by increasing its capacity.
The increase ANP release was not sufficient to decrease maternal arterial blood pressure, but may counteract vasospasm locally in the maternal and uteroplacental circulation
American Psychological Association (APA)
al-Muraba, Hani Ahmad Ibrahim& Abd al-Al, Fatimah Ahmad& Fathi, Julnar Muhammad& Sayyid, Jihan Ahmad& Abd al-Al, Diya al-Din Muhammad& Makki, Abd al-Rahim Muhammad Abd al-Hafiz. 2005. Preeclampsia : the effect of iiitravenous fluid preload on vasoactive peptide secretion during caesarean section under spinal anaesthesia. Assiut Medical Journal،Vol. 29, no. 2, pp.109-124.
https://search.emarefa.net/detail/BIM-51841
Modern Language Association (MLA)
al-Muraba, Hani Ahmad Ibrahim…[et al.]. Preeclampsia : the effect of iiitravenous fluid preload on vasoactive peptide secretion during caesarean section under spinal anaesthesia. Assiut Medical Journal Vol. 29, no. 2(May. 2005), pp.109-124.
https://search.emarefa.net/detail/BIM-51841
American Medical Association (AMA)
al-Muraba, Hani Ahmad Ibrahim& Abd al-Al, Fatimah Ahmad& Fathi, Julnar Muhammad& Sayyid, Jihan Ahmad& Abd al-Al, Diya al-Din Muhammad& Makki, Abd al-Rahim Muhammad Abd al-Hafiz. Preeclampsia : the effect of iiitravenous fluid preload on vasoactive peptide secretion during caesarean section under spinal anaesthesia. Assiut Medical Journal. 2005. Vol. 29, no. 2, pp.109-124.
https://search.emarefa.net/detail/BIM-51841
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 121-124
Record ID
BIM-51841