Efficient three-component synthesis of 3, 4-disubstituted isoxazol-5(4H)-ones in green media
Joint Authors
Kiyani, Hamzah
Jabbari, Murtada
Mosallanezhad, Asiyeh
Source
Issue
Vol. 9, Issue 4 (31 Dec. 2014), pp.279-288, 10 p.
Publisher
Yarmouk University Deanship of Research and Graduate Studies
Publication Date
2014-12-31
Country of Publication
Jordan
No. of Pages
10
Main Subjects
Abstract EN
Several derivatives of 3,4-disubstituted isoxazol-5(4H)-ones were synthesized via a onepot, three-component cyclocondensation reaction of hydroxylamine hydrochloride, various aryl aldehydes and β-oxoesters.
The process takes place in water at room temperature.
Tetrabutylammonium perchlorate (TBAP), sodium oxalate or glycine act as catalysts in promoting this reaction.
The merits of this method are its efficiency, simplicity, cleanness, greenness, easy work-up, high chemical yields, recyclability, avoidance of using organic solvents, as well as the relatively short reaction times.
American Psychological Association (APA)
Kiyani, Hamzah& Jabbari, Murtada& Mosallanezhad, Asiyeh. 2014. Efficient three-component synthesis of 3, 4-disubstituted isoxazol-5(4H)-ones in green media. Jordan Journal of Chemistry،Vol. 9, no. 4, pp.279-288.
https://search.emarefa.net/detail/BIM-519592
Modern Language Association (MLA)
Kiyani, Hamzah…[et al.]. Efficient three-component synthesis of 3, 4-disubstituted isoxazol-5(4H)-ones in green media. Jordan Journal of Chemistry Vol. 9, no. 4 (Dec. 2014), pp.279-288.
https://search.emarefa.net/detail/BIM-519592
American Medical Association (AMA)
Kiyani, Hamzah& Jabbari, Murtada& Mosallanezhad, Asiyeh. Efficient three-component synthesis of 3, 4-disubstituted isoxazol-5(4H)-ones in green media. Jordan Journal of Chemistry. 2014. Vol. 9, no. 4, pp.279-288.
https://search.emarefa.net/detail/BIM-519592
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 287-288
Record ID
BIM-519592
