Radiologial changes associated with antiphospholipid syndrome
Other Title(s)
التغيرات الإشعاعية المصاحبة لمتلازمة المتضادات الدهون الفسفورية
Joint Authors
al-Azraqi, Tariq A.
al-Shehri, Abd al-Rahman
Shalabi, Midhat
Badri, Ala
Source
Egyptian Rheumatology and Rehabilitation
Issue
Vol. 29, Issue 4 (31 Jul. 2002), pp.677-692, 16 p.
Publisher
The Egyptian Society for Rheumatology and Rehabilitation
Publication Date
2002-07-31
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Topics
Abstract AR
أجري هذا البحث على سبعة عشر مريضا يعانون صن متلازمة متضادات الدهون الفسفورية لبيان التغيرات الإشعاعية المصاحبة لهذه المتلازمة و أسباب حدوثها و وضع نظام علاجي و وقائي لها لتلافي تكرار الأعراض المرضية.
Abstract EN
Aim of work: To demonstrate the radiological changes associated with the vascular manifestations that occur in antiphospholipid syndrome patients.
Patients & Methods: This study was conducted on 17 patients who fulfilled the criteria for diagnosis of anti-phospholipid syndrome (APS).
They were eleven patients diagnosed as primary APS and six patients as secondary APS (five systemic lupus erythematosus patients and one polyarteritis nodosa).
All patients were subjected to detailed medical history taking, neurological and thrombotic data.
Those patients with predisposing thrombotic factors like diabetes mellitus, atherosclerosis etc..
were excluded from the study.
Laboratory investigation in included medium or high titer level of anticardiolipin antibodies (aCL) and/or positive lupus anticoagulant (LAC) test.
Imaging studies included angiographic assessment (carotid, flush aortic and mesenteric), venogram for venous system and CT in selected cases.
Results: Of the 17 patients who were included in this study, 28 thromboembolic vascular events were recorded in the form of recurrent pulmonary embolism (17.6%), non-occlusive superior mesenteric artery narrowing (11.8%), external iliac artery embolism (5.9%), renal artery thrombosis(5.9),renal artery fibromuscular dysplasia (5.9%),cerebral artery embolism (23.5), coronary artery embolism(11.8), superficial femoral artery embolism(5.9), popliteal artery embolism(5.9), recurrent superficial femoral and popliteal DVT(64.7).
Conclusion: Antiphospholipid syndrome is a complicated disease that affects any age.
It is characterized by recurrent abortions and thromboembolic manifestations within both the venous and arterial systems.
Organ damage and functional impairment may be the end-result.
Early diagnosis, a patient presenting with a first thrombotic event should be screened for anticardiolipin antibodies and/or lupus anticoagulants and adequate anticoagulation therapy for the thromboembolic manifestation may be life saving.
American Psychological Association (APA)
Shalabi, Midhat& al-Azraqi, Tariq A.& Badri, Ala& al-Shehri, Abd al-Rahman. 2002. Radiologial changes associated with antiphospholipid syndrome. Egyptian Rheumatology and Rehabilitation،Vol. 29, no. 4, pp.677-692.
https://search.emarefa.net/detail/BIM-52289
Modern Language Association (MLA)
al-Azraqi, Tariq A.…[et al.]. Radiologial changes associated with antiphospholipid syndrome. Egyptian Rheumatology and Rehabilitation Vol. 29, no. 4 (Jul. 2002), pp.677-692.
https://search.emarefa.net/detail/BIM-52289
American Medical Association (AMA)
Shalabi, Midhat& al-Azraqi, Tariq A.& Badri, Ala& al-Shehri, Abd al-Rahman. Radiologial changes associated with antiphospholipid syndrome. Egyptian Rheumatology and Rehabilitation. 2002. Vol. 29, no. 4, pp.677-692.
https://search.emarefa.net/detail/BIM-52289
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 690-692
Record ID
BIM-52289