Measurement of anti-cyclic citrullinated peptide, leptin hormone, and lipoprotein (a) in Iraqi female patients with rheumatoid arthritis
Joint Authors
Rashid, Manal Kamal
Mahmud, Halla G.
Abd al-Qahar, Zaynah H.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 56, Issue 3 (30 Sep. 2014), pp.305-307, 3 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2014-09-30
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Topics
Abstract EN
Background : Rheumatoid arthritis is one of the most common forms of inflammatory polyarthritis, with a prevalence of approximately 0.8 % of adults worldwide, Rheumatoid arthritis patients may become disabled within few years if untreated that may lead to permanent disability.
Different biomarkers have been assessed for the improved diagnosis of Rheumatoid arthritis, including a wide range of autoantibodies.
However, only rheumatoid factor (RF) and anti-cyclic citrullinated peptide (ACCP) have gained wide acceptance.
Aim of the study to investigate the levels of ACCR Leptin, and Lipoprotein (a) in females with RA to provideinformation on possible pathophysiologic mechanisms, and to give recommendations for determination of these parameters in diagnosis and follow up of Rheumatoid arthritis patients.
Patients and methods : The study included Forty women with RA and Thirty apparently healthy women with matching age and weight as controls.
The patients were selected at the outpatient clinic of Rheumatology & Rehabilitation in Medical City / Baghdad Teaching Hospital during the period from (May 2013 ) to (December 2013).
Results : The results showed that levels of ACCP antibodies in serum of patients with RA were significantly higher than in serum of healthy control.
Also there were significant differences between mean of serum leptin level and Lp (a) in patients compared to the control group.
Conclusion : Serum biomarkers like ACCR Leptin, & Lipoprotein (a) assays are becoming increasingly available and may help in early diagnosis and assessment of complications in Rheumatoid arthritis patients.
American Psychological Association (APA)
Abd al-Qahar, Zaynah H.& Mahmud, Halla G.& Rashid, Manal Kamal. 2014. Measurement of anti-cyclic citrullinated peptide, leptin hormone, and lipoprotein (a) in Iraqi female patients with rheumatoid arthritis. Journal of the Faculty of Medicine Baghdad،Vol. 56, no. 3, pp.305-307.
https://search.emarefa.net/detail/BIM-526817
Modern Language Association (MLA)
Abd al-Qahar, Zaynah H.…[et al.]. Measurement of anti-cyclic citrullinated peptide, leptin hormone, and lipoprotein (a) in Iraqi female patients with rheumatoid arthritis. Journal of the Faculty of Medicine Baghdad Vol. 58, no. 3 (2014), pp.305-307.
https://search.emarefa.net/detail/BIM-526817
American Medical Association (AMA)
Abd al-Qahar, Zaynah H.& Mahmud, Halla G.& Rashid, Manal Kamal. Measurement of anti-cyclic citrullinated peptide, leptin hormone, and lipoprotein (a) in Iraqi female patients with rheumatoid arthritis. Journal of the Faculty of Medicine Baghdad. 2014. Vol. 56, no. 3, pp.305-307.
https://search.emarefa.net/detail/BIM-526817
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 306-307
Record ID
BIM-526817